Natural Product Inhibitors of Hsp90: Potential Leads for Drug Discovery
نویسندگان
چکیده
منابع مشابه
High-Throughput Screen of Natural Product Libraries for Hsp90 Inhibitors
Hsp90 has become the target of intensive investigation, as inhibition of its function has the ability to simultaneously incapacitate proteins that function in pathways that represent the six hallmarks of cancer. While a number of Hsp90 inhibitors have made it into clinical trials, a number of short-comings have been noted, such that the search continues for novel Hsp90 inhibitors with superior ...
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ژورنال
عنوان ژورنال: Mini-Reviews in Medicinal Chemistry
سال: 2009
ISSN: 1389-5575
DOI: 10.2174/138955709787316056